Activation of tissue transglutaminase transcription by histone deacetylase inhibition as a therapeutic approach for Myc oncogenesis

Histone deacetylase (HDAC) inhibitors reactivate tumor suppressor gene transcription; induce cancer cell differentiation, growth arrest, and programmed cell death; and are among the most promising new classes of anticancer drugs. Myc oncoproteins can block cell differentiation and promote cell proli...

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Detalhes bibliográficos
Main Authors: Liu, Tao, Tee, Andrew E. L., Porro, Antonio, Smith, Stewart A., Dwarte, Tanya, Liu, Pei Yan, Iraci, Nunzio, Sekyere, Eric, Haber, Michelle, Norris, Murray D., Diolaiti, Daniel, Della Valle, Giuliano, Perini, Giovanni, Marshall, Glenn M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2141837/
https://ncbi.nlm.nih.gov/pubmed/18003922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0705524104
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