Direct and Coordinate Regulation of ATP-binding Cassette Transporter Genes by Myc Factors Generates Specific Transcription Signatures That Significantly Affect the Chemoresistance Phenotype of Cancer Cells

Increased expression of specific ATP-binding cassette (ABC) transporters is known to mediate the efflux of chemotherapeutic agents from cancer cells. Therefore, establishing how ABC transporter genes are controlled at their transcription level may help provide insight into the role of these multifac...

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Bibliografiske detaljer
Main Authors: Porro, Antonio, Haber, Michelle, Diolaiti, Daniel, Iraci, Nunzio, Henderson, Michelle, Gherardi, Samuele, Valli, Emanuele, Munoz, Marcia A., Xue, Chengyuan, Flemming, Claudia, Schwab, Manfred, Wong, Jason H., Marshall, Glenn M., Della Valle, Giuliano, Norris, Murray D., Perini, Giovanni
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2010
Fag:
Gene Regulation
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2885232/
https://ncbi.nlm.nih.gov/pubmed/20233711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.078584
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