Загрузка...
Engineering Thrombin for Selective Specificity toward Protein C and PAR1
Thrombin elicits functional responses critical to blood homeostasis by interacting with diverse physiological substrates. Ala-scanning mutagenesis of 97 residues covering 53% of the solvent accessible surface area of the enzyme identifies Trp(215) as the single most important determinant of thrombin...
Сохранить в:
| Главные авторы: | , , , , |
|---|---|
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Biochemistry and Molecular Biology
2010
|
| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2885193/ https://ncbi.nlm.nih.gov/pubmed/20404340 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.119875 |
| Метки: |
Добавить метку
Нет меток, Требуется 1-ая метка записи!
|