Potent aquaretic agent. A novel nonpeptide selective vasopressin 2 antagonist (OPC-31260) in men.

Solute-free water diuretics (aquaretics) by antagonizing hydrosmotic vasopressin receptors (V2) may be useful in treating water-retaining diseases. The effects of intravenous administration of a newly developed nonpeptide, selective V2 antagonist, OPC-31260, at doses ranging from 0.017 to 1.0 mg/kg...

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Main Authors: Ohnishi, A, Orita, Y, Okahara, R, Fujihara, H, Inoue, T, Yamamura, Y, Yabuuchi, Y, Tanaka, T
Format: Artigo
Jezik:Inglês
Izdano: 1993
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC288462/
https://ncbi.nlm.nih.gov/pubmed/8254021
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