Potent aquaretic agent. A novel nonpeptide selective vasopressin 2 antagonist (OPC-31260) in men.

Solute-free water diuretics (aquaretics) by antagonizing hydrosmotic vasopressin receptors (V2) may be useful in treating water-retaining diseases. The effects of intravenous administration of a newly developed nonpeptide, selective V2 antagonist, OPC-31260, at doses ranging from 0.017 to 1.0 mg/kg...

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Bibliografische gegevens
Gepubliceerd in:J Clin Invest
Hoofdauteurs: Ohnishi, A, Orita, Y, Okahara, R, Fujihara, H, Inoue, T, Yamamura, Y, Yabuuchi, Y, Tanaka, T
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Clinical Investigation 1993
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Research Article
Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC288462/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8254021/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI116881
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