A Yersinia secreted effector protein promotes virulence by preventing inflammasome recognition of the type III secretion system

Pattern recognition receptors (PRRs) detect conserved microbial structures generally absent from eukaryotes. Bacterial pathogens commonly utilize pore-forming toxins or specialized secretion systems to deliver virulence factors that promote bacterial replication by modulating host cell physiology. D...

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Detalhes bibliográficos
Main Authors: Brodsky, Igor E., Palm, Noah W., Sadanand, Saheli, Ryndak, Michelle B., Sutterwala, Fayyaz S., Flavell, Richard A., Bliska, James B., Medzhitov, Ruslan
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2883865/
https://ncbi.nlm.nih.gov/pubmed/20478539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2010.04.009
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