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Reduced Secretion of YopJ by Yersinia Limits In Vivo Cell Death but Enhances Bacterial Virulence

Numerous microbial pathogens modulate or interfere with cell death pathways in cultured cells. However, the precise role of host cell death during in vivo infection remains poorly understood. Macrophages infected by pathogenic species of Yersinia typically undergo an apoptotic cell death. This is du...

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Bibliografske podrobnosti
Main Authors: Brodsky, Igor E., Medzhitov, Ruslan
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2361194/
https://ncbi.nlm.nih.gov/pubmed/18483548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000067
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