Recovery of phospho-ERK activity allows melanoma cells to escape from BRAF inhibitor therapy

BACKGROUND: Resistance to BRAF inhibitors is an emerging problem in the melanoma field. Strategies to prevent and overcome resistance are urgently required. METHODS: The dynamics of cell signalling, BrdU incorporation and cell-cycle entry after BRAF inhibition was measured using flow cytometry and w...

Descripció completa

Guardat en:
Dades bibliogràfiques
Autors principals: Paraiso, K H T, Fedorenko, I V, Cantini, L P, Munko, A C, Hall, M, Sondak, V K, Messina, J L, Flaherty, K T, Smalley, K S M
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2010
Matèries:
Translational Therapeutics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2883709/
https://ncbi.nlm.nih.gov/pubmed/20531415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6605714
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars