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Beyond BRAF: where next for melanoma therapy?

In recent years, melanoma has become a poster-child for the development of oncogene-directed targeted therapies. This approach, which has been exemplified by the development of small-molecule BRAF inhibitors and the BRAF/MEK inhibitor combination for BRAF-mutant melanoma, has brought new hope to pat...

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Detalhes bibliográficos
Publicado no:Br J Cancer
Main Authors: Fedorenko, I V, Gibney, G T, Sondak, V K, Smalley, K S M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4453440/
https://ncbi.nlm.nih.gov/pubmed/25180764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2014.476
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