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Integrating BRAF/MEK inhibitors into combination therapy for melanoma

The discovery of BRAF mutations in melanoma has not yet translated into clinical success, suggesting that BRAF/MEK inhibitors will need to be combined with other agents. In the current review, we discuss other pathways likely to be important for melanoma progression and suggest possible drug combina...

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Bibliografische gegevens
Hoofdauteurs: Smalley, K S M, Flaherty, K T
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2009
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2658537/
https://ncbi.nlm.nih.gov/pubmed/19156138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6604891
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