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Risk factors for MEK-associated retinopathy in patients with advanced melanoma treated with combination BRAF and MEK inhibitor therapy

BACKGROUND: Retinopathy is a common adverse event with mitogen-activated extracellular signal-regulated kinase (MEK) inhibitors. Little is known about the pathophysiology of MEK inhibitor-associated retinopathy (MEKAR). Since MEKAR has many similarities to central serous chorioretinopathy (CSCR), th...

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Detalhes bibliográficos
Publicado no:Ther Adv Med Oncol
Main Authors: Booth, Andrew E. C., Hopkins, Ashley M., Rowland, Andrew, Kichenadasse, Ganessan, Smith, Justine R., Sorich, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7406936/
https://ncbi.nlm.nih.gov/pubmed/32821295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1758835920944359
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