Recent advances in the treatment of melanoma with BRAF and MEK inhibitors

Selective inhibition of the mitogen activated protein kinase (MAPK) pathway with either BRAF or MEK inhibition has emerged as the key component for the treatment of BRAF-mutant metastatic melanoma. New evidence from several phase III trials suggests that the combination of BRAF and MEK inhibitors im...

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Detalhes bibliográficos
Publicado no:Ann Transl Med
Main Authors: Muñoz-Couselo, Eva, García, Jesús Soberino, Pérez-García, José Manuel, Cebrián, Vanesa Ortega, Castán, Javier Cortés
Formato: Artigo
Idioma:Inglês
Publicado em: AME Publishing Company 2015
Assuntos:
Review Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4583602/
https://ncbi.nlm.nih.gov/pubmed/26488003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3978/j.issn.2305-5839.2015.05.13
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