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Updates and challenges on treatment with BRAF/MEK-inhibitors in melanoma

INTRODUCTION: Breakthroughs in targeted therapy have significantly improved outcomes for many patients with advanced melanoma, including those with BRAFV600 mutant disease. Targeted therapy for BRAFV600-mutant metastatic melanoma includes combinations of BRAF inhibitors and MEK inhibitors, which imp...

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Vydáno v:Expert Opin Orphan Drugs
Hlavní autoři: Eroglu, Zeynep, Ozgun, Alpaslan
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6296476/
https://ncbi.nlm.nih.gov/pubmed/30574432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21678707.2018.1512402
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