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Paradoxical oncogenesis and the long term consequences of BRAF inhibition in melanoma

The clinical benefits of BRAF inhibition in patients with advanced-stage BRAF-mutant melanoma are now well established. Although the emergence of cutaneous squamous cell carcinomas (SCCs) and secondary melanomas in patients on BRAF-inhibitor therapy have been well described, reports are emerging of...

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Detalhes bibliográficos
Main Authors: Gibney, Geoffrey T., Messina, Jane L., Fedorenko, Inna V., Sondak, Vernon K., Smalley, Keiran S.M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3983565/
https://ncbi.nlm.nih.gov/pubmed/23712190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrclinonc.2013.83
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