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An unholy alliance: co-operation between BRAF and NF1 in melanoma development and BRAF inhibitor resistance
In this issue of Cancer Discovery, two studies provide new evidence implicating loss of the tumor suppressor NF1 in the biological behavior of cutaneous melanoma. The first study from Maertens and colleagues describes a new transgenic mouse model in which mutant BRAF co-operates with NF1 loss to dri...
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| 主要な著者: | , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3595124/ https://ncbi.nlm.nih.gov/pubmed/23475878 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-13-0017 |
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