RecQ Promotes Toxic Recombination in Cells Lacking Recombination-Intermediate-Removal Proteins

The RecQ-helicase family is widespread, highly conserved, and includes human orthologues that suppress genomic instability and cancer. In vivo, some RecQ homologues promote reduction of steady-state levels of bimolecular recombination intermediates (BRIs), which block chromosome segregation if not r...

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Bibliographic Details
Main Authors: Magner, Daniel B., Blankschien, Matthew D., Lee, Jennifer A., Pennington, Jeanine M., Lupski, James R., Rosenberg, Susan M.
Format: Artigo
Language:Inglês
Published: 2007
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2881834/
https://ncbi.nlm.nih.gov/pubmed/17466628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2007.03.012
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