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Manipulating Mitotic Recombination in the Zebrafish Embryo Through RecQ Helicases
RecQ DNA helicases resolve Rad-51-mediated recombination and suppress aberrant homologous recombination. RecQ gene loss is associated with cancer susceptibility and increased mitotic recombination. We have developed an in vivo assay based on a zebrafish pigment mutant for suppression of RecQ activit...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Genetics Society of America
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1894594/ https://ncbi.nlm.nih.gov/pubmed/17483412 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.107.072983 |
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