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RecQ Promotes Toxic Recombination in Cells Lacking Recombination-Intermediate-Removal Proteins
The RecQ-helicase family is widespread, highly conserved, and includes human orthologues that suppress genomic instability and cancer. In vivo, some RecQ homologues promote reduction of steady-state levels of bimolecular recombination intermediates (BRIs), which block chromosome segregation if not r...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2881834/ https://ncbi.nlm.nih.gov/pubmed/17466628 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2007.03.012 |
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