Sgs1 RecQ Helicase Inhibits Survival of Saccharomyces cerevisiae Cells Lacking Telomerase and Homologous Recombination

In yeast telomerase mutants, the Sgs1 RecQ helicase slows the rate of senescence and also facilitates the appearance of certain types of survivors of critical telomere shortening via mechanisms dependent on Rad52-dependent homologous recombination (HR). Here we describe a third function for Sgs1 in...

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Detalhes bibliográficos
Main Authors: Lee, Julia Y., Mogen, Jonathan L., Chavez, Alejandro, Johnson, F. Brad
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
Assuntos:
DNA: Replication, Repair, Recombination, and Chromosome Dynamics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2573055/
https://ncbi.nlm.nih.gov/pubmed/18757364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M804760200
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