A fast mathematical programming procedure for simultaneous fitting of assembly components into cryoEM density maps

Motivation: Single-particle cryo electron microscopy (cryoEM) typically produces density maps of macromolecular assemblies at intermediate to low resolution (∼5–30 Å). By fitting high-resolution structures of assembly components into these maps, pseudo-atomic models can be obtained. Optimizing the q...

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Bibliografiske detaljer
Main Authors: Zhang, Shihua, Vasishtan, Daven, Xu, Min, Topf, Maya, Alber, Frank
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2010
Fag:
Ismb 2010 Conference Proceedings July 11 to July 13, 2010, Boston, Ma, Usa
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2881386/
https://ncbi.nlm.nih.gov/pubmed/20529915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btq201
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