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Inferential optimization for simultaneous fitting of multiple components into a cryoEM map of their assembly

Models of macromolecular assemblies are essential for a mechanistic description of cellular processes. Such models are increasingly obtained by fitting atomic-resolution structures of components into a density map of the whole assembly. Yet, current density-fitting techniques are frequently insuffic...

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Détails bibliographiques
Auteurs principaux: Lasker, Keren, Topf, Maya, Sali, Andrej, Wolfson, Haim J.
Format: Artigo
Langue:Inglês
Publié: 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2680734/
https://ncbi.nlm.nih.gov/pubmed/19233204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2009.02.031
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