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A fast mathematical programming procedure for simultaneous fitting of assembly components into cryoEM density maps

Motivation: Single-particle cryo electron microscopy (cryoEM) typically produces density maps of macromolecular assemblies at intermediate to low resolution (∼5–30 Å). By fitting high-resolution structures of assembly components into these maps, pseudo-atomic models can be obtained. Optimizing the q...

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Detalhes bibliográficos
Main Authors: Zhang, Shihua, Vasishtan, Daven, Xu, Min, Topf, Maya, Alber, Frank
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2881386/
https://ncbi.nlm.nih.gov/pubmed/20529915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btq201
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