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Determining macromolecular assembly structures by molecular docking and fitting into an electron density map

Structural models of macromolecular assemblies are instrumental for gaining a mechanistic understanding of cellular processes. Determining these structures is a major challenge for experimental techniques, such as X-ray crystallography, NMR spectroscopy and electron microscopy. Thus, computational m...

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Bibliographic Details
Main Authors: Lasker, Keren, Sali, Andrej, Wolfson, Haim J.
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2952722/
https://ncbi.nlm.nih.gov/pubmed/20827723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.22845
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