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Cleavage of IgGs by proteases associated with invasive diseases: An evasion tactic against host immunity?
The effective functioning of immunoglobulins and igG mAbs in removing pathological cells requires that the antigen binding regions and the Fc (effector) domain act in concert. The hinge region that connects these domains itself presents motifs that engage Fc receptors on immune effector cells to ach...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Landes Bioscience
2010
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2881249/ https://ncbi.nlm.nih.gov/pubmed/20400859 |
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