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Preparing an Oncolytic Poliovirus Reombinant for Clinical Application Against Glioblastoma Multiforme

PVS-RIPO is a genetically recombinant, non-pathogenic poliovirus chimera with a tumor-specific conditional replication phenotype. Consisting of the genome of the live attenuated poliovirus type 1 (Sabin) vaccine with its cognate IRES element replaced with that of human rhinovirus type 2, PVS-RIPO di...

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Detalhes bibliográficos
Main Authors: Goetz, Christian, Gromeier, Matthias
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2881183/
https://ncbi.nlm.nih.gov/pubmed/20299272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cytogfr.2010.02.005
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