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Oncolytic poliovirus against malignant glioma

In cancerous cells, physiologically tight regulation of protein synthesis is lost, contributing to uncontrolled growth and proliferation. We describe a novel experimental cancer therapy approach based on genetically recombinant poliovirus that targets an intriguing aberration of translation control...

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Detalhes bibliográficos
Main Authors: Goetz, Christian, Dobrikova, Elena, Shveygert, Mayya, Dobrikov, Mikhail, Gromeier, Matthias
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3187927/
https://ncbi.nlm.nih.gov/pubmed/21984883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/fvl.11.76
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