MAPK Signal-integrating Kinase Controls Cap-independent Translation and Cell Type-specific Cytotoxicity of an Oncolytic Poliovirus

Many animal viruses exhibit proficient growth in transformed cells, a property that has been harnessed for the development of novel therapies against cancer. Despite overwhelming evidence for this phenomenon, understanding of the molecular mechanisms enabling tumor-cell killing is rudimentary for mo...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Goetz, Christian, Everson, Richard G, Zhang, Linda C, Gromeier, Matthias
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2010
Schlagworte:
Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2990508/
https://ncbi.nlm.nih.gov/pubmed/20648000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2010.145
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