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Oncolytic Immunotherapy Through Tumor-specific Translation and Cytotoxicity of Poliovirus

Achieving tumor-specific, robust, and durable effector cytotoxic immune responses is key to successful immunotherapy. This has been accomplished with adoptive cell transfer of ex vivo-expanded autologous tumor-infiltrating or engineered T cells, or with immune checkpoint inhibitors, enhancing inhere...

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Detalhes bibliográficos
Publicado no:Discov Med
Main Authors: Brown, Michael C., Gromeier, Matthias
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4780852/
https://ncbi.nlm.nih.gov/pubmed/26105699
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