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Cytotoxic and Immunogenic Mechanisms of Recombinant Oncolytic Poliovirus
An oncolytic virus (OV) based on poliovirus (PV), the highly attenuated polio-/rhinovirus recombinant PVSRIPO, may deliver targeted inflammatory cancer cell killing; a principle that is showing promise in clinical trials for recurrent glioblastoma (GBM). The two decisive factors in PVSRIPO anti-tumo...
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| Publicado en: | Curr Opin Virol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4550519/ https://ncbi.nlm.nih.gov/pubmed/26083317 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coviro.2015.05.007 |
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