Recombinant oncolytic poliovirus, PVSRIPO, has potent cytotoxic and innate inflammatory effects, mediating therapy in human breast and prostate cancer xenograft models

Intratumoral inoculation of viruses with tumor-selective cytotoxicity may induce cancer cell death and, thereby, shrink neoplastic lesions. It is unlikely, however, that viral tumor cell killing alone could produce meaningful, durable clinical responses, as clinically suitable ‘oncolytic’ viruses ar...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Oncotarget
Egile Nagusiak: Holl, Eda K., Brown, Michael C., Boczkowski, David, McNamara, Megan A., George, Daniel J., Bigner, Darell D., Gromeier, Matthias, Nair, Smita K.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Impact Journals LLC 2016
Gaiak:
Research Paper
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5346754/
https://ncbi.nlm.nih.gov/pubmed/27806313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12975
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