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Preparing an Oncolytic Poliovirus Reombinant for Clinical Application Against Glioblastoma Multiforme
PVS-RIPO is a genetically recombinant, non-pathogenic poliovirus chimera with a tumor-specific conditional replication phenotype. Consisting of the genome of the live attenuated poliovirus type 1 (Sabin) vaccine with its cognate IRES element replaced with that of human rhinovirus type 2, PVS-RIPO di...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2010
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2881183/ https://ncbi.nlm.nih.gov/pubmed/20299272 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cytogfr.2010.02.005 |
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