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Thermodynamic Characterization of DNA with 3-Deazaadenine and 3-Methyl-3-Deazaadenine Substitutions: The Effect of Placing a Hydrophobic Group in the Minor Groove of DNA

In many high-resolution structures of DNA there are ordered waters associated with the floor of the minor groove and extending outward in several layers. It is thought that this hydration structure, along with cations, reduces the Coulombic repulsion of the interstrand phosphates. In previous studie...

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書目詳細資料
Main Authors: Ganguly, Manjori, Wang, Ruo-Wen, Marky, Luis A., Gold, Barry
格式: Artigo
語言:Inglês
出版: 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2880643/
https://ncbi.nlm.nih.gov/pubmed/20469878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp101004k
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