A Bridging Water Anchors the Tethered 5-(3-Aminopropyl)-2′-deoxyuridine Amine in the DNA Major Groove Proximate to the N+2 C·G Base Pair: Implications for Formation of Interstrand 5′-GNC-3′ Cross-Links by Nitrogen Mustards

Site-specific insertion of 5-(3-aminopropyl)-2′-deoxyuridine (Z3dU) and 7-deaza-dG into the Dickerson-Drew dodecamers 5′-d(C(1)G(2)C(3)G(4)A(5)A(6)T(7)T(8)C(9)Z(10)C(11)G(12))-3′ · 5′-d(C(13)G(14)C(15)G(16)A(17)A(18)T(19)T(20-)C(21)Z(22)C(23)G(24))-3′ (named DDD(Z10)) and 5′-d(C(1)G(2)C(3)G(4)A(5)A(...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Wang, Feng, Li, Feng, Ganguly, Manjori, Marky, Luis A., Gold, Barry, Egli, Martin, Stone, Michael P.
Formato: Artigo
Idioma:Inglês
Publicado: 2008
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2730145/
https://ncbi.nlm.nih.gov/pubmed/18549246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi800375m
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares