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Site-Specific Stabilization of DNA by a Tethered Major Groove Amine, 7-Aminomethyl-7-deaza-2′-deoxyguanosine
[Image: see text] A cationic 7-aminomethyl-7-deaza-2′-deoxyguanosine (7amG) was incorporated site-specifically into the self-complementary duplex d(G(1)A(2)G(3)A(4)X(5)C(6)G(7)C(8)T(9)C(10)T(11)C(12))(2) (X = 7amG). This construct placed two positively charged amines adjacent to the major groove edg...
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| Autors principals: | , , , , |
|---|---|
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American
Chemical Society
2013
|
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3812902/ https://ncbi.nlm.nih.gov/pubmed/24131376 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi400695r |
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