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A shared mechanism for lipid- and β-subunit-coordinated stabilization of the activated K(+) channel voltage sensor
The low-dielectric plasma membrane provides an energy barrier hindering transmembrane movement of charged particles. The positively charged, voltage-sensing fourth transmembrane domain (S4) of voltage-gated ion channels must surmount this energy barrier to initiate channel activation, typically nece...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Federation of American Societies for Experimental Biology
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2879946/ https://ncbi.nlm.nih.gov/pubmed/20040519 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.09-145219 |
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