Regulation of Voltage-Activated K(+) Channel Gating by Transmembrane β Subunits

Voltage-activated K(+) (K(V)) channels are important for shaping action potentials and maintaining resting membrane potential in excitable cells. K(V) channels contain a central pore-gate domain (PGD) surrounded by four voltage-sensing domains (VSDs). The VSDs will change conformation in response to...

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Autores principales: Sun, Xiaohui, Zaydman, Mark A., Cui, Jianmin
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Research Foundation 2012
Materias:
Pharmacology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3328208/
https://ncbi.nlm.nih.gov/pubmed/22529812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2012.00063
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