Modulation of voltage-gated K(+) channels by the sodium channel β1 subunit

Voltage-gated sodium (Na(V)) and potassium (K(V)) channels are critical components of neuronal action potential generation and propagation. Here, we report that Na(V)β1 encoded by SCN1b, an integral subunit of Na(V) channels, coassembles with and modulates the biophysical properties of K(V)1 and K(V...

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Autors principals: Nguyen, Hai M., Miyazaki, Haruko, Hoshi, Naoto, Smith, Brian J., Nukina, Nobuyuki, Goldin, Alan L., Chandy, K. George
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2012
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3494885/
https://ncbi.nlm.nih.gov/pubmed/23090990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1209142109
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