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Structure and Function of the Influenza A M2 Proton Channel

The M2 protein of influenza A viruses forms a tetrameric pH-activated proton-selective channel that is targeted by the amantadine class of anti-viral drugs. Its ion channel function has been extensively studied by electrophysiology and mutagenesis; however, the molecular mechanism of proton transpor...

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Библиографические подробности
Главные авторы: Cady, Sarah D., Luo, Wenbin, Hu, Fanghao, Hong, Mei
Формат: Artigo
Язык:Inglês
Опубликовано: 2009
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2879269/
https://ncbi.nlm.nih.gov/pubmed/19601584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi9008837
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