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Conformational Plasticity of the Influenza A M2 Transmembrane Helix in Lipid Bilayers Under Varying pH, Drug Binding and Membrane Thickness

Membrane proteins change their conformations to respond to environmental cues, thus conformational plasticity is important for function. The influenza A M2 protein forms an acid-activated proton channel important for the virus lifecycle. Here we have used solid-state NMR spectroscopy to examine the...

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書誌詳細
主要な著者: Hu, Fanghao, Luo, Wenbin, Cady, Sarah D., Hong, Mei
フォーマット: Artigo
言語:Inglês
出版事項: 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2997931/
https://ncbi.nlm.nih.gov/pubmed/20883664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2010.09.014
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