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The Energetics of Transmembrane Helix Insertion into a Lipid Bilayer
Free energy profiles for insertion of a hydrophobic transmembrane protein α-helix (M2 from CFTR) into a lipid bilayer have been calculated using coarse-grained molecular dynamics simulations and umbrella sampling to yield potentials of mean force along a reaction path corresponding to translation of...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2955506/ https://ncbi.nlm.nih.gov/pubmed/20959094 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.08.002 |
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