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Structure and Function of the Influenza A M2 Proton Channel
The M2 protein of influenza A viruses forms a tetrameric pH-activated proton-selective channel that is targeted by the amantadine class of anti-viral drugs. Its ion channel function has been extensively studied by electrophysiology and mutagenesis; however, the molecular mechanism of proton transpor...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2879269/ https://ncbi.nlm.nih.gov/pubmed/19601584 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi9008837 |
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