Caricamento...

Molecular determinants of coupling between the domain III voltage-sensor and pore of a sodium channel

In a voltage-dependent sodium channel, the activation of voltage-sensors upon depolarization leads to the opening of pore gates. To elucidate the principles underlying this conformational coupling, we investigated a putative gating interface in domain III of the sodium channel using voltage-clamp fl...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Muroi, Yukiko, Arcisio-Miranda, Manoel, Chowdhury, Sandipan, Chanda, Baron
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2879147/
https://ncbi.nlm.nih.gov/pubmed/20118934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.1749
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !