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Transfusion of red blood cells after prolonged storage produces harmful effects that are mediated by iron and inflammation
Although red blood cell (RBC) transfusions can be lifesaving, they are not without risk. In critically ill patients, RBC transfusions are associated with increased morbidity and mortality, which may increase with prolonged RBC storage before transfusion. The mechanisms responsible remain unknown. We...
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Main Authors: | , , , , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society of Hematology
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2879099/ https://ncbi.nlm.nih.gov/pubmed/20299509 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-10-245001 |
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