Toll-like receptor 2 signaling in CD4(+) T lymphocytes promotes T helper 17 responses and regulates the pathogenesis of autoimmune disease

Toll-like receptors (TLRs) have previously been shown to play critical roles in the activation of innate immunity. Here, we describe that T cell expression of TLR2 regulates T helper 17 (Th17) cell responses. Stimulation with TLR2 agonists promoted Th17 differentiation in vitro and led to more robus...

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Detalhes bibliográficos
Main Authors: Reynolds, Joseph M., Pappu, Bhanu P., Peng, Juan, Martinez, Gustavo J., Zhang, Yongliang, Chung, Yeonseok, Ma, Li, Yang, Xuexian O., Nurieva, Roza I., Tian, Qiang, Dong, Chen
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2878917/
https://ncbi.nlm.nih.gov/pubmed/20434372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2010.04.010
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