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Toll-like receptor 4 signaling in T cells promotes autoimmune inflammation

Toll-like receptors (TLRs) are critical components of innate immunity and function as rapid pathogen sensors. TLR4 is expressed on CD4(+) T cells as well, the functional significance of which is unclear. In this study, we analyzed the function of TLR4 in T cells but did not find a role in promoting...

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Detalhes bibliográficos
Main Authors: Reynolds, Joseph M., Martinez, Gustavo J., Chung, Yeonseok, Dong, Chen
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3420161/
https://ncbi.nlm.nih.gov/pubmed/22826216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1120585109
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