Negative regulation of Toll-like-receptor signaling by IRF-4

The recognition of microbial components by Toll-like receptors (TLRs) is an event central to the activation of innate and adaptive immune systems. TLR activation triggers the induction of downstream target genes, wherein the TLR-interacting adaptor molecule MyD88 recruits various signaling molecules...

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Bibliografske podrobnosti
Main Authors: Negishi, Hideo, Ohba, Yusuke, Yanai, Hideyuki, Takaoka, Akinori, Honma, Kiri, Yui, Katsuyuki, Matsuyama, Toshifumi, Taniguchi, Tadatsugu, Honda, Kenya
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2005
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1257749/
https://ncbi.nlm.nih.gov/pubmed/16236719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0508327102
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