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Negative regulation of Toll-like-receptor signaling by IRF-4
The recognition of microbial components by Toll-like receptors (TLRs) is an event central to the activation of innate and adaptive immune systems. TLR activation triggers the induction of downstream target genes, wherein the TLR-interacting adaptor molecule MyD88 recruits various signaling molecules...
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| Hoofdauteurs: | , , , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
National Academy of Sciences
2005
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1257749/ https://ncbi.nlm.nih.gov/pubmed/16236719 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0508327102 |
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