Evidence for licensing of IFN-γ-induced IFN regulatory factor 1 transcription factor by MyD88 in Toll-like receptor-dependent gene induction program

The recognition of microbial components by Toll-like receptors (TLRs) initiates signal transduction pathways, which trigger the expression of a series of target genes. It has been reported that TLR signaling is enhanced by cytokines such as IFN-γ, but the mechanisms underlying this enhancement remai...

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Detalhes bibliográficos
Main Authors: Negishi, Hideo, Fujita, Yasuyuki, Yanai, Hideyuki, Sakaguchi, Shinya, Ouyang, Xinshou, Shinohara, Masahiro, Takayanagi, Hiroshi, Ohba, Yusuke, Taniguchi, Tadatsugu, Honda, Kenya
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1586247/
https://ncbi.nlm.nih.gov/pubmed/17018642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0607181103
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