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Understanding the development and function of T follicular helper cells

A fundamental function of T helper (Th) cells is to regulate B-cell proliferation and immunoglobulin class switching, especially in the germinal centers. Th1 and Th2 lineages of CD4(+) T cells have long been considered to play an essential role in helping B cells by promoting the production immunogl...

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Bibliographic Details
Main Authors: Nurieva, Roza I, Chung, Yeonseok
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4002918/
https://ncbi.nlm.nih.gov/pubmed/20383172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2010.24
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