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Cutting Edge: In Vitro Generated Th17 Cells Maintain Their Cytokine Expression Program in Normal but Not Lymphopenic Hosts

Upon activation, naive CD4(+) T cells differentiate into effector Th cell subsets. The stability and plasticity of effector Th cells have not been well understood. In this study we used an IL-17F-red fluorescent protein reporter mouse to analyze the plasticity of Th17 cells in vitro and in vivo. We...

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Bibliografiske detaljer
Main Authors: Nurieva, Roza, Yang, Xuexian O., Chung, Yeonseok, Dong, Chen
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2755098/
https://ncbi.nlm.nih.gov/pubmed/19234148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0803931
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