Generation of follicular helper T cells is mediated by IL-21 but independent of TH1, TH2 or TH17 lineages

After activation, CD4+ helper T (TH) cells differentiate into distinct effector lineages. Although CXCR5+ follicular TH (T(FH)) cells are important in humoral immunity, their developmental regulation is unclear. Here we show that T(FH) cells have a distinct gene expression profile from other effecto...

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Hlavní autoři: Nurieva, Roza I., Chung, Yeonseok, Hwang, Daehee, Yang, Xuexian O., Kang, Hong Soon, Ma, Li, Wang, Yi-hong, Watowich, Stephanie S., Jetten, Anton M., Tian, Qiang, Dong, Chen
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2556461/
https://ncbi.nlm.nih.gov/pubmed/18599325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2008.05.009
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